According to a recent journal article I read, allyl amines are among the most useful of synthetic intermediates. I happen to agree. If only there were a convenient and cost-effective way to make these compounds. Let me think. OK. Amines are good nucleophiles. And allyl halides are great electrophiles. Maybe if I mixed those together, I could get my precious allyl amine.
No. You idiot. That is way too complicated. There is a MUCH easier way. Just mix this "simple" gold catalyst with your amine and an allene at 100 degrees for 12 hours. And BAM! you got an allyl amine.
But wait you ask. What about other allenes than the one in the abstract picture above. Don't worry, they tried those too.
Finally, an easy way to make N-allyl morpholine! Check out the awesome E/Z selectivity with unsymmetrical allenes! Allenes as starting materials, what a great idea! They are so easy to make, especially these low molecular weight ones!
The world was waiting for a solution to this long standing problem in organic chemistry. Thank you for this. Nobel! Nobel!
Tip of the hat to Dr. B. Mike O'Keefe for pointing out this gem.