Usually, in my extensive experience, named reactions work pretty well. I mean they wouldn't be famous reactions if they worked like shit. Right?
That brings me to the Reimer-Tiemann reaction. This thing sucks. In my particular case, the reaction was a complete disaster. Here is a generic version of the reaction if you are not familiar with it (everyone out there except Jason).
In an effort to optimize this reaction, I consulted a recent review. Here are some of the accolades from the article.
"Even 105 years after its discovery, conditions for the Reimer-Tiemann reaction cannot said to have been optimized. This is not too surprising for a reaction in which a quantitative yield has never been reported, and in which useful yields of 3-10% are not unususal."
Nice. I guess I should have consulted this before embarking on a route invoving the "Reamed"-Tiemann reaction. Any other suggestions for the worst named reaction?